Activate Epicardial Repair
These ammonium persulfate-loaded carboxylic gelatin-methacrylate nanoparticles induce epithelial-mesenchymal transition of WT1+ epicardial cells via simultaneous activation of autophagy and mTOR pathway, promoting cardiac repair after myocardial infarction.
Kong, Fanxuan · Cai, Liu · Tian, Ye · Hou, Honghao · Wang, Leyu · Qiu, Xiaozhong
ACS Nano 2023
Significantly improved cardiac function after myocardial infarction
Induced transformation of WT1+ epicardial cells into endothelial-like cells in vitro