Chemotactic chaperone nanomotors

Crossing the blood-brain barrier

Nanomotors that sense an iNOS gradient to both dissolve α-synuclein aggregates and prevent misfolding, offering a new strategy for Parkinson's disease treatment.

Wenjing, Wang · Chen, Yu · Yao, Zhang · Chen, Lin · Mao, Chun · Wan, Mimi

Science Advances 2025