MnO₂ nanoflowers

Boosts CRISPR intracellular sensing

These MnO₂ nanoflowers co-deliver CRISPR/Cas12a components intracellularly and release Mn²⁺ to enhance trans-cleavage activity for efficient biosensing.

Xiao-Ming, Sun · Kang, Yafeng · He, Jingwei · Tang, Hong Wu · Liu, Da · Li, Chengyu

Sensors and Actuators, B: Chemical 2024

Advantages

Ultrasensitive detection of microRNA-21

Near-infrared light activation for spatiotemporal control

Efficient imaging in live cells and bodies