Bridged bicyclo[m.3.1] compounds

Up to 85% yield, 97% ee

Highly enantioselective construction of chiral bridged bicyclic skeletons via intramolecular Diels-Alder reaction, enabling efficient access to [4.3.1] and [5.3.1] ring systems.

Kai, Liu · Zhao, Zhengxing · Qin, Wenling · Liu, Yidong · Yan, Hailong

Chemical Communications 2024

Specifications

分离收率最高

{'zh': '85', 'en': ''} %

对映选择性最高

{'zh': '97', 'en': ''} %