Ligand-Free and Solvent-Free
A ruthenium-based catalytic system that achieves highly chemoselective decarbonylative coupling of indole esters with arylboronic acids without ligands, bases, or organic solvents.
Zhang, Jin · Jiaojiao, Zhang · Yan, Wenxuan · Nana, Chen · Shang, Linqin · Jiaojiao, Wu · Szostak, Michal L.
ACS Sustainable Chemistry & Engineering 2026
First ruthenium-catalyzed decarbonylative cross-coupling under mechanochemical conditions
No added ligands, bases, or organic solvents
Highly chemoselective coupling with common arylboronic acids