Intranasal anti-asthma
A Mycobacterium tuberculosis-derived fusion protein that significantly alleviates airway inflammation in allergic asthma via intranasal immunization, with no significant damage to major organs.
Wang, Jing · Zhang, Wei · Ma, Rui · Ma, Gang · Wang, Na · Qin, Yanyan · Wang, Peng · Wan, Qiaofeng
International Journal of Biological Macromolecules 2024
Significantly alleviated airway inflammation
Reduced proportions of anaphylaxis-related cells in lungs
No significant histopathological injury to major organs
Complement and coagulation cascades and phagosomes significantly enriched at both gene and protein levels