Fluoromethylation Reagent

New route to allenes

A reagent system that introduces fluoromethyl groups into enynes under visible light to afford di- and trisubstituted allenes.

Pan, Yingjie · Chen, Xiaoyun · Yu, Huaguang · Han, Ying · Sun, Qiu · Hou, Hong · Zhu, Shaoqun

Organic Letters 2024

Advantages

Access to diverse di- and trisubstituted allenes under mild conditions

Large-scale reaction demonstrated