Overcomes bone metastasis resistance
Bone-targeting nanoparticles co-encapsulating kaempferol and cisplatin release drugs in the acidic tumor microenvironment to inhibit fatty acid metabolism, thereby overcoming drug resistance in lung cancer bone metastasis.
Hu, Peng · Meng, Tong · Yan, Wangjun · Zhou, Lei · Wang, Changping · Song, Dianwen
Journal of Nanobiotechnology 2025
Surface-modified with poly-aspartic acid for bone targeting
Release in acidic tumor microenvironment