NM2e Lipid Nanovaccine

Cross-protection >90%

A nanovaccine based on cationic solid lipid nanoadjuvant loaded with NM2e antigen, inducing robust humoral and cellular immune responses and providing over 90% cross-protection against homo- and heterosubtype influenza viruses.

Gao, Yuan · Han, Shulan · Liu, Qi · Yang, Jun Wei · Wang, Wenling · Jing-jing, Zhang · Ju, Ruijun · Shen, Xiaoling · Tan, Wenjie · Wang, Lianyan

ACS Nano 2024

Specifications

树突状细胞抗原摄取提高

{'zh': '约4', 'en': ''} 倍

in lymph nodes

{'zh': '', 'en': '>14'} days

Cross-protection efficiency

{'zh': '', 'en': '>90'} %

Advantages

Induced IgG2a/IgG1 ratio significantly higher than NM2e