Chiral Sulfinyl Compounds via Asymmetric Deoxygenation of Sulfones

High Enantioselectivity

A synergistic organocatalytic and cyano-group strategy enables highly enantioselective deoxygenation of sulfones, providing an innovative route to chiral sulfinyl compounds.

Huang, Shengli · Zeng, Zhen · Zhang, Nan · Qin, Wenling · Lan, Yu · Yan, Hailong

Nature Chemistry 2023