Para-Selective Nitrobenzene Amination Reagent

Transition-metal-free, high selectivity

A transition-metal-free, highly para-selective C-N coupling approach via recombination of aminyl radical and nitrobenzene complex radical, compatible with diverse amines and nitroarenes.

Zhen, Zhang · Yue, Shusheng · Yang, Ruchun · Wang, Shengchun · Zhang, Tianqi · Sun, Li · Lei, Aiwen · Cai, Hu

Nature Communications 2024

Specifications

产率高

{'zh': '96', 'en': ''} %

Advantages

Exclusive para-selectivity

Transition-metal-free

Mild conditions