2-Pyrrolidinone-Functionalized Phenanthridines

Metal-Free Synthesis

These compounds are synthesized via an NHC-catalyzed radical tandem reaction under metal- and oxidant-free conditions, offering a new route to phenanthridine-based functional molecules.

Zhou, Nengneng · Wang, Lei · Zhao, Fangli · Xiang, Gao · Xiaowei, Zhao · Zhang, Man

Journal of Organic Chemistry 2023

Advantages

Metal- and oxidant-free conditions

Broad substrate scope and good functional group compatibility