Phase Angle-Responsive Light-Addressable Electrochemical Sensor

Label-free single-cell adhesion imaging

This sensor overcomes conventional amplitude-based limitations by utilizing phase angle detection, enabling label-free quantitative imaging of single-cell adhesion across diverse cell types and substrates.

Meng, Yao · Wang, Sen · Jiale, Li · Shang, Yun · Wang, Jian · Zhuang, Jian · Zhang, Dewen

Analytical Chemistry 2025

Advantages

Label-free detection

Single-cell resolution

Applicable to diverse cell types and semiconductor substrates