Antifungal-active molecules
Electrochemically synthesized gem-difluoroalkene derivatives with antifungal activity for drug discovery.
Yue, Fuyang · Jiayi, Li · Song, Hongjian · Liu, Yuxiu · Wang, Qingmin
Green Chemistry 2025
Synthesized under mild, transition-metal-free, sacrificial-anode-free conditions
Broad substrate applicability and excellent compatibility with complex functional groups
Enables late-stage diversification of natural products, biomolecules, and pharmaceuticals
Several active compounds exhibited antifungal activity