Promotes Cardiomyocyte Differentiation
The primate-specific ERVH48-1 protein binds and degrades the WNT antagonist SFRP2 to relieve WNT inhibition and promote cardiomyocyte differentiation.
Ran, Zhang · Xiang, Dan · Zhu, Jieying · Zhang, Qi · Zhong, Hui · Peng, Yuling · Ma, Gang · Ye, Weipeng · Shi, Ruona · Zhou, Xuemeng · Babarinde, Isaac Adeyemi · Su, Huanxing · Chen, Jiekai · Zhang, Xiaofei · Qin, Dajiang · Hutchins, Andrew Paul · Pei, Duanqing · Li, Dongwei
Cell Stem Cell 2024