Bacteria-Responsive DNAzyme

One sequence, two bacteria

A single DNAzyme sequence can be switched between Klebsiella pneumoniae and Escherichia coli responses solely by changing reaction conditions, avoiding a new selection.

Li, Xiaoqian · Xue, Wei · Li, Zhi · Zhang, Rui · Li, Jiuxing · Chang, Yangyang · Liu, Meng

Angewandte Chemie - International Edition 2026

Specifications

pneumoniae at pH

{'zh': '约6600', 'en': '6,'} kobs

比肺炎克雷伯菌高

{'zh': '约520', 'en': ''} 倍

In clinical samples

{'zh': '88.9', 'en': '88.9'} %