Lipopolysaccharide Binding Protein

Anti-lipid peroxidation

Lipopolysaccharide binding protein sequesters unsaturated triglycerides into lipid droplets via its lipid-capture activity, protecting hepatocytes from peroxidative injury under oxidative stress.

Qilun, Zhang · Xuting, Shen · Xin, Yuan · Huang, Jing · Zhu, Yaling · Tengteng, Zhu · Tao, Zhang · Haibo, Wu · Qian, Wu · Yinguang, Fan · Jing, Ni · Meng, Leilei · He, Anyuan · Shi, Chaowei · Hao, Li · Qingsong, Hu · Jian, Wang · Chang, Cheng · Huang, Fan · Li, Fang · Meng, Chen · Liu, Anding · Ye, Shandong · Zheng, Mao · Fang, Haoshu

Nature Communications 2024

Advantages

Significantly upregulates lipopolysaccharide-binding protein expression

N-acetyl-L-cysteine treatment reduces triglycerides accumulation

Chronic stress leads to insulin resistance and obesity