Ethylene signaling switch
MHZ3 interacts with ethylene receptors and OsCTR2 to stabilize the signaling complex and maintain OsCTR2 phosphorylation, while ethylene treatment disrupts the complex to initiate downstream signaling.
Li, Xinkai · Yi-Hua, Huang · Zhao, Rui · Cao, Wu Qiang · Lu, Long · Jia, Han · Zhou, Yang · Zhang, Xun · Wu, Ai · Tao, Jian · Wei, Wei · Zhang, Wanke · Chen, Shouyi · Ma, Biao · Yin, Cuicui · Zhang, Jinsong
Nature Communications 2024
MHZ3 physically interacts with both subfamily I and II ethylene receptors (e.g., OsERS2 and OsETR2)
MHZ3 stabilizes receptor association with OsCTR2 and maintains OsCTR2 activity
Ethylene treatment disrupts the MHZ3/receptors/OsCTR2 complex and reduces OsCTR2 phosphorylation