UGT Enzyme

A detoxification enzyme that directly degrades fenpropathrin, conferring resistance to pyrethroid insecticides in silkworms, with a conserved mechanism applicable across pest species.

Yi, Zheng Yang · Zhang, Ying · Zhang, Qiang · Jun-li, Lv · Qin, Sheng · Sun, Xia · Wang, Xueyang · Dai, Li · Li, Muwang

Insect Molecular Biology 2024

Advantages

significant decrease in cell activity after knockdown

significant increase in cell activity after overexpression

significant reduction in fenpropathrin residues after 12 h incubation with recombinant enzyme

significant reduction in resistance after knockdown in Spodoptera exigua