100% protection in mice
Co-delivers three immunodominant antigens with a STING agonist adjuvant for comprehensive and durable immunity.
Yu, Weili · Shen, Lijuan · Yilong, Yang · Qi, Jinming · Hu, Tao
International Journal of Biological Macromolecules 2025
100% protection against lethal ectromelia virus challenge in BALB/c mice after triple immunization
No observed organ toxicity
Induced balanced Th1/Th2 cytokine profiles
Induced robust CD4⁺ and CD8⁺ T-cell responses