TaIAA25 Alkaline Sensitivity Regulator

Enhances alkaline tolerance in wheat

Modulates proton pump activity to boost alkaline tolerance, offering a new breeding target.

Yin, Fengxiang · Cui, Minghan · Liu, Jianing · Liu, Yue · Shao-Zhu, Chen · Wei, Lin · Zhou, Qing · Xia, Guangmin Qing · Liu, Shuwei

Proceedings of the National Academy of Sciences of the United States of America 2026

Advantages

Overexpression significantly increases sensitivity to alkaline treatment

Knockout mutants display enhanced alkaline tolerance

Directly interacts with the P domain of TaHA2 and blocks proton efflux