Sr/Ca co-deposited coating

Osteogenic and antibacterial

A multifunctional composite coating with strontium and calcium, fabricated via redox-assisted co-deposition on zinc implants, offering simultaneously osteogenic and antibacterial properties while regulating zinc ion release.

Guorui, Zhang · Wang, Changping · Yingfan, Guo · Wu, Jianfeng · Nie, Huali · Wang, Cong

Colloids and Surfaces B: Biointerfaces 2026

Specifications

Coating fabrication time

{'zh': '30', 'en': '30'} min

Advantages

Rapid fabrication

The coating is completed within 30 minutes, greatly reducing the time cost for implant surface treatment.

Mild conditions, no special equipment

It proceeds at mild temperature and atmospheric pressure without specialized equipment, lowering the technical barrier and suitable for scaling.

Both osteogenic and antibacterial

The coating promotes osteogenic activity by activating osteogenesis-related signaling pathways and stimulating cell adhesion, spreading, migration, and differentiation, while also conferring antibacterial properties.

Regulates zinc release to reduce toxicity

The coating regulates the degradation behavior of the Zn substrate and modulates Zn2+ release kinetics to mitigate cytotoxicity from excessive local ion concentrations.

Applications

• Surface modification of orthopedic implants：Offers a simple and fast coating method to replace complex processes for functionalizing orthopedic implant surfaces.
• Biodegradable metal implants：Improves biocompatibility of zinc-based biodegradable implants by controlling degradation and ion release via the coating.
• Antibacterial coatings for implants：Endows implant surfaces with antibacterial properties to reduce infection risk without antibiotics.
• Bone tissue engineering scaffolds：Promotes osteointegration through osteogenic activity, suitable for surface modification of bone tissue engineering scaffolds.