Remodels cold tumor immune microenvironment
Co-delivers a TLR7/8 agonist and a photosensitizer in a hyaluronic acid-modified liposome for active tumor targeting and pH-responsive release, combining photodynamic and chemodynamic therapy to remodel the cold tumor immune microenvironment.
Yikai, Ma · Minghao, Sun · Chunyu, Qu · Siran, Jin · Ziqing, Yang · Hongjie, Liu · Wang, Zhiqiang · Wu, Xiaodan · Hao, Chuncheng · Jin, Yingxue
Chemical Engineering Journal 2026
Significantly inhibits both primary and distant tumors
Safe for normal tissues