DNAzyme-Driven Detection System

3 live bacteria in one snapshot

Combines bacterial protein recognition with rolling-circle amplification and molecular beacon encoding to distinguish and quantify three live bacteria in a single smartphone image.

Xue, Wei · Li, Ran · Wang, Kun · Song, Kaiyun · Chang, Yangyang · Liu, Meng

Angewandte Chemie - International Edition 2026

Specifications

positive
{'zh': '100', 'en': '≥95.2'} %

Advantages

Sensitivity of 10¹–10² CFU/mL for S. aureus, B. cocovenenans, and E. coli

Correctly identified 29/32 naturally contaminated samples in a 32-tube array