Double S-shaped quadruple helicene-like molecules

up to 96% e.e.

Organocatalytic asymmetric synthesis of quadruple helicene-like molecules with catalyst-controlled absolute configuration, offering an efficient route to higher-order helicenes.

Huang, Shengli · Wen, Haojun · Qin, Wenling · Wang, Pengfei · Lan, Yu · Shiqi, Jia · Yan, Hailong

Nature Communications 2025

Specifications

对映选择性高

{'zh': '96', 'en': ''} %

Advantages

both (P,P,P,P) and (M,M,M,M) configurations accessible by modulating catalyst structure

double S-shaped quadruple helicene-like molecules