Suppresses HIF-2α
A sesquiterpene with an unprecedented skeleton that suppresses renal cancer-related HIF-2α signaling without apparent cytotoxicity.
Chen, Hong · Guo, Miao · Lu, Guo · Luo, Di · Zhu, Qian · Wu, Rui · Zhan, Zhajun · Dong-Xu, Wang · Ma, Liefeng
Journal of Natural Products 2025
Inhibited HIF-2α-regulated endothelial cell tube formation at 5 μM
No apparent cytotoxicity