Dual-Channel Discrimination of Bio-thiols
An acridine-conjugated indole salt-based probe that distinguishes Cys, Hcy, and GSH via dual-channel and time-dependent fluorescence, addressing the challenge of discriminating structurally similar bio-thiols.
Min, Zhou · Lin, Yanfei · Bai, Tianwen · Tianqing, Ye · Zeng, Yanbo · Li, Lei · Zhaosheng, Qian · Guo, Longhua · Liu, Haiying · Wang, Jianbo
Sensors and Actuators, B: Chemical 2024
Under 488 nm excitation, significant turn-on NIR fluorescence response toward Cys at 654 nm with a large Stokes shift of about 166 nm
Under 640 nm excitation, turn-on NIR fluorescence response for Hcy/GSH at 695 nm
Successful intracellular imaging of endogenous and exogenous bio-thiols in living cells