pDEP-DLD Raman Flow Sorter

105 mutants in 2 days

A Raman-activated cell sorter combining positive dielectrophoresis and deterministic lateral displacement that focuses, traps, and functionally sorts fast-moving single cells in a wide channel, preserving full vitality without labeling.

Wang, Xixian · Wang, Sen · Zhidian, Diao · Gong, Yanhai · Sun, Qing Qing · Zhang, Jiaping · Ren, Lihui · Li, Yuandong · Ji, Yuetong · Shen, Wei · Huang, Shi · Song, Xiaojin · Cui, Qiu · Feng, Yingang · Xu, Jian · Ma, Bo

Proceedings of the National Academy of Sciences of the United States of America 2025

Specifications

sorting accuracy

{'zh': '> 90', 'en': '> 90'} %

throughput

{'zh': '~ 600', 'en': '~ 600'} events min⁻¹

yield

{'zh': '> 85', 'en': '> 85'} %

产量提高

{'zh': '58', 'en': ''} %

Advantages

stable running ~ 10 h