Gas-Driven Flow Focusing Sample Introduction Device

Clog-free single-cell introduction

A plug-and-play sample introduction device for mass cytometry based on gas-driven flow focusing, using a virtual hole to generate a liquid jet and achieving monodispersion via jet breakup, eliminating the conventional nebulizer and preventing capillary clogging; compatible with mass cytometry or ICP-MS.

Liu, Jinhui · Xu, Haitao · Weiliang, Liu · Xing, Zhi · Tang, Fei · Zhang, Sichun · Zhang, Xinrong

Analytical Chemistry 2025

Advantages

Plug-and-play

High-speed microscopy verified monodispersion

Results highly consistent with conventional nebulizer

Four element calibration beads and cell samples