89Zr-Labeled PD-1/VEGF Bispecific Antibody

Dual-target tumor imaging

A radiolabeled bispecific antibody probe targeting both PD-1 and VEGF for noninvasive tumor imaging.

Jiang, Yang · Hou, Xingguo · Siqi, Hao · Chen, Qian · Zhang, Qian · Zhang, Yan · Yang, Zhi · Zhu, Hua

Journal of Medicinal Chemistry 2026

Specifications

Radiochemical purity

{'zh': '>99', 'en': '>99'} %

In vitro stability

{'zh': '>95', 'en': '>95'} %

for PD- Kd

{'zh': '6.92', 'en': '6.92'} nM

for VEGF-A Kd

{'zh': '82.48', 'en': '82.48'} nM

Advantages

Elimination half-life 35.14 h