8× Oxygen Exchange Efficiency
The chip recapitulates rapid oxygen dynamics of intestinal IR injury, enabling identification of OLFM4 as a therapeutic target.
Huang, Jinjian · Xu, Ziyan · Chen, Jiao · Li, Zongan · Li, Sicheng · Liu, Ye · Li, Ze · Qu, Guiwen · Wu, Jie · Zhao, Yun · Chen, Kang · Li, Jieshou · Pan, Yichang · Wu, Xiuwen · Ren, Jianan
Bioactive Materials 2023
Oxygen exchange efficiency eight times that of conventional tri-gas incubator
Intestinal organoids reproducing all types of intestinal epithelial cells
Exhibit metabolic disorder, inflammatory reaction, and cell apoptosis upon hypoxia/reoxygenation
First identification of Olfm4 as the most significantly down-regulated gene under rapid HR