Dual CAT and POD activity
An artificial green catalyst made of peptide, DNA and hemin that decomposes hydrogen peroxide and degrades dyes simultaneously, outperforming the natural bifunctional enzyme KatG.
Qiu, Dehui · Zhang, Xiaobo · Tian, Fan · Liu, Yuan · He, Fangni · 72856381 · Wei, Shijiong · Mergny, Jean-Louis · Monchaud, David · Zhang, Shujuan · Ju, Huangxian · Zhou, Jun
National Science Review 2026
Turnover number (kcat) of optimized bi-CPDzyme prototype (G-quadruplex-Hemin-HRRHKHRRH) surpasses natural CAT/POD bifunctional enzyme KatG
Competes with individual CAT and POD enzymes
Achieves efficient decomposition of bleaching-derived residual H2O2 in water-/energy-saving manner
Degrades dyes from textile industry effluents even in complex real samples
Easily recyclable and implementable