Phage-Derived Hyaluronate Lyase

86% Higher Extracellular Activity

Signal peptide engineering enables efficient extracellular expression in Bacillus subtilis, markedly enhancing hyaluronan degradation with excellent thermal and pH stability.

Li, Shubo · Jiang, Yu · Zhi, Yao · Qing, Li · Liu, Qiang · Jin-Song, Shi · Xu, Hong · Gong, Jingsong

Applied Biochemistry and Biotechnology 2024

Specifications

摇瓶培养胞外酶活从

{'zh': '1.0 × 10⁴', 'en': ''} U/mL

发酵罐分批发酵胞外酶活

{'zh': '1.07 × 10⁵', 'en': ''} U/mL

Advantages

Significant stability in the range of 40 °C and pH 4-8

Optimum conditions at 40 °C and pH 6