Oral thrombus targeting
Turns portal vein blockage into an advantage for oral delivery, co-loading a chemotherapeutic and an anticoagulant for effective, low-toxicity PVTT therapy.
Chen, Xiangjun · Li, Lu · Fan, Qing · Zhang, Lingyu · Li, Wenting · Hong, Wei · Wang, Chungang · Zhang, Xiuping
Nano Letters 2025
Encapsulating doxorubicin hydrochloride and low molecular weight heparin
Oral administration achieves excellent antitumor effects with minimal side effects