Low-Crystallinity Prussian Blue Nanoparticles

Reduction Overload Antitumor

Exploits tumor cells' redox sensitivity via high SOD-like activity to induce reduction overload, suppressing heat shock proteins to enhance photothermal therapy.

Yuxin, Yao · Yao, Junlie · Lai, Liangxue · Chenglong, He · Jiang, Shaohua · Elsayad, Kareem · Peng, Hao · Wu, Aiguo · Yang, Fang

Small 2025

Advantages

High SOD-like activity

Induces reduction overload

Down-regulates heat shock proteins

Inhibits tumor growth