Dual pH & enzyme responsive
Releases gold nanoclusters only when both an acidic environment and the target enzyme are present, enabling AND logic sensing with minimal background.
Chen, Kaili · Loynachan, Colleen N. · Thanapongpibul, Chalaisorn · Ma, Liyun · Yeow, Jonathan · Najer, Adrian · Stevens, Molly
ACS Sensors 2025
Stable encapsulation under physiological conditions, release under acidic conditions
AND logic gate minimizes background signal