Ir(III) Complex Photosensitizer

Enhanced toxicity upon light

A cyclometalated iridium complex with two-photon absorption, exhibiting significantly enhanced cytotoxicity against MCF-7 tumor cells upon light irradiation, and the ability to modulate reactive oxygen species for differential photodynamic therapy.

Jiang, Qin · Yang, Xinda

RSC Advances 2024

Specifications

双光子吸收截面最大

{'zh': '215', 'en': ''} GM

at nm excited

{'zh': '567', 'en': '-850'} nm

Advantages

Phototoxicity index PI > 50

Mainly generates superoxide anion (O2•−)