Microbubble cavity stereo-optical sensor

Label-free single-molecule detection

Integrates a microbubble optofluidic channel into a Fabry-Pérot cavity to three-dimensionally tailor the intra-cavity light field, enabling specific biomolecular detection without pre-modification.

Zhao, Xuyang · Guo, Zhihe · Zhou, Yi · Guo, Junhong · Liu, Zhiran · Luo, Man · Li, Yuxiang · Wang, Qi · Zhang, Meng · Xi, Yang · Wang, You · Sun, Yunlu · Wu, Xiang

Biosensors and Bioelectronics 2023

Specifications

折射率灵敏度

{'zh': '679', 'en': ''} nm/RIU

Refractive index resolution

{'zh': '950', 'en': '-7'} RIU

for human IgG

{'zh': '5', 'en': '0.5'} pg/mL

Advantages

Quality factor ~10^5