Optimized substrate tunnel gating
Tailoring IL chain length on CNT carriers tunes CALB adsorption orientation and substrate tunnel gating, enhancing enzyme activity and stability.
Lu, Zeping · Nian, Binbin · Hu, Yi
International Journal of Biological Macromolecules 2023
IL chain length significantly affects CALB adsorption orientation
Leu278 flip stabilizes open state of Tunnel 2
Strong interactions (vdW and hbond) between ILs and CNTs