Gold-Based Heterostructure Nanozyme

Photothermal and catalytic synergy

A gold-based heterostructure nanozyme combining photothermal effect and dual enzyme-mimicking activities for synergistic catalytic-photothermal osteosarcoma therapy in acidic tumor microenvironment.

Xing, Zhang · Xiang, Li · Fu, Mengying · MacHuki, Jeremiah Ong Achwa · Wang, Wandong · Liang, Wu · Qun, Zhao · Xin, Ning · Lei, Hua · Gao, Fenglei

Chemical Engineering Journal 2024

Specifications

Photothermal conversion efficiency

{'zh': '', 'en': '73.6'} %

Michaelis constant Km

{'zh': '39.56', 'en': '39.56'} mM

Advantages

No lung metastasis in in vivo xenograft osteosarcoma model

Simultaneously decomposes H₂O₂ into ·OH and replenishes O₂