Reverses hepatic oxidative damage
Selenocysteine-loaded nanoparticles actively target hepatocytes after glycyrrhetinic acid modification and restore endogenous antioxidant enzymes in two acute liver injury models, providing liver protection.
Zhou, Yanfeng · Sun, Jinli · Wang, Shanshan · Hu, Xingjie · Chen, Nan
Cell Proliferation 2023
Significantly decreased hepatic lipid peroxidation levels in APAP- and CCl₄-induced ALI mouse models
Significantly decreased tissue vacuolization and serum liver transaminase levels
Prominently increased levels of endogenous antioxidant enzymes