Hyaluronic Acid Supramolecular Hydrogel

pH/temperature dual-responsive release

Built on a hyaluronic acid backbone that enables active tumor targeting, this hydrogel delivers drugs with reduced cytotoxicity to liver cells.

Li, Caixia · Zhou, Qin · Haoliang, Huang · Li, Liang

Supramolecular Chemistry 2024

Advantages

DOX@G[5, 10, 5] showed higher cytotoxicity toward SKOV-3 cells than HepG2 cells

Release kinetics fitted Higuchi and Korsmeyer-Peppas models