Plant Phosphate Coordination Hydrogel

Zunlei, Gong; Xiao, Tianhua; Wu, Dan; Yu, Hui; Yu, Cai; Jiamin, Liu; Dongming, Duan; Tan, Guoxing; Ning, Chengyun; Wang, Le; Zhou, Lei

Plant Phosphate Coordination Hydrogel

Rebalances osteoclast/osteoblast

An injectable adhesive hydrogel that degrades in the osteoporotic microenvironment to release phytic acid and magnesium ions, synergistically inhibiting osteoclastogenesis and promoting osteoblast differentiation to restore bone homeostasis.

Zunlei, Gong · Xiao, Tianhua · Wu, Dan · Yu, Hui · Yu, Cai · Jiamin, Liu · Dongming, Duan · Tan, Guoxing · Ning, Chengyun · Wang, Le · Zhou, Lei

ACS Nano 2025

Specifications

弯曲阻力较单纯髓内固定提高: {'zh': '84.6', 'en': ''} %

Advantages

Firmly adheres to irregular bone surfaces at the fracture site

Degrades in the acidic osteoporotic microenvironment