Dual-responsive titanium implant

Early antibacterial, late osteogenesis

ROS/pH-responsive release of antibacterial agent and sustained Sr2+ release enable spatiotemporal antibacterial and osteo-immunomodulatory functions with enhanced osseointegration.

Wang, Qing · Gao, Ya · Wang, Xuan · Pei, Qingguo · Zhang, Taiyu · Wang, Changping · Pan, Jinsong

Advanced healthcare materials 2024

Advantages

Responsive release for antibacterial and immunomodulation

Sr2+ release in acidic environment

Antibacterial and osteogenic effects in vitro and in vivo