Faster Cu-catalyzed trifluoromethylation
Introducing an oxygen coordination site at the 2-position of 1,10-phenanthroline significantly shortens the reaction time for Cu-catalyzed trifluoromethylation of aryl iodides and extends the scope to various aryl bromides.
Wu, Peng · Liu, Xuefen · Luo, Shuping
Journal of Organic Chemistry 2026
Significantly shortened reaction time
Improved conversion efficiency
Applicable to various aryl bromides