Hybrid Nanowire-Nanopipette Sensor

Real-time single-cell monitoring

For the first time, enables real-time, quantitative monitoring of lysosomal glycosidase secretion from living macrophages while maintaining cell viability.

Qi, Ting · Wang, Xiao · Gao, Rui · Chen, Ying · Tian, Yu · Zhang, Li · Zhang, Xin · Huang, Weihua

Journal of the American Chemical Society 2026

Advantages

Single-cell level

Real-time monitoring

Maintains cell viability