Dual-responsive drug release
A Pluronic F127-modified hyaluronic acid hydrogel that responds to both pH and reduction, targets SKOV-3 cancer cells, and releases doxorubicin with superior anticancer efficacy over free drug.
Li, Caixia · Qin, Zhou · Zhenzhen, Chao · Li, Liang
Arabian Journal for Science and Engineering 2025
Exhibited more significant anticancer effects than free DOX on SKOV-3 cells
Release kinetics fitted Korsmeyer-Peppas model indicating non-Fickian diffusion