Improves lung compliance
An adeno-associated virus vector-based gene therapy agent that delivers the Dkk1 gene to simultaneously inhibit Wnt/β-catenin signaling and oxidative stress, alleviating silicotic lesions and improving lung function, offering an alternative to adenoviral vectors for silicosis treatment.
Ma, Jia · Wang, Jiaqi · Sun, Ruiting · Zhaojun, Wang · Xue, Jing · Wu, Shuang · Hu, Wenfeng · Wang, Jing · Cai, Qian · Chen, Juan · Liu, Xiaoming
Antioxidants and Redox Signaling 2024
Alleviation of silicotic lesions
Improvement of pulmonary compliance
Improvement of radiological findings