Genetically Engineered VLP Probe

In-vivo miRNA Imaging

Via virus-like particle targeting and multibranched DNA scaffold signal enrichment, it achieves ultrasensitive and specific detection of cancer-related microRNA, enabling imaging in living cells and in vivo.

Chen, Yaling · Wang, Xiaomei · Tang, Hongwu · Li, Chengyu

Biosensors and Bioelectronics 2023

Advantages

Ultra-sensitive and specific to miRNA-155

Enables imaging of low-abundance analytes in living cells and bodies