Magnetic field-driven biofilm penetration
Under a magnetic field, these nanoparticles physically penetrate and disrupt periodontal biofilms, enabling deep drug delivery and bacterial eradication while maintaining good biocompatibility.
Tong, Fei · Wang, Pei · Chen, Zhiqiang · Yihan, Liu · Lianguo, Wang · Guo, Jun · Li, Zhihua · Cai, Hu · Wei, Junchao
International journal of nanomedicine 2023
Exhibit intense anti-biofilm activity against periodontal biofilms
Kill bacteria deep in biofilms both in vivo and in vitro
Disrupt biofilm integrity under magnetic field, improving drug penetration
Well-recovered periodontal inflammation in rat periodontitis models